Order Rogaine

What is Rogaine?

Minoxidil. In studies of external application of the drug under the name "Rogain" stimulated a moderate growth of hair in 29% of men. According to the manufacturer, "super" agent minoxidil 45% effective.

Preparations with different concentrations of minoxidil are sold in pharmacies without a prescription. However, they are not in all cases, luxurious head of hair is not given, and the first results appear only after 4 months of twice-daily rubbing. And use it too, have life, and if you stop using, then all that had grown rapidly fall. Medicinal properties of this drug for the treatment of hair loss was discovered quite by accident.

Originally, this drug has been developed for lowering blood pressure, but during his trial, it emerged that he has an unexpected and valuable effect - to stimulate hair growth. It was found that Minoxidil directly affects the cell structure and cell activity of hair follicles. Relaxing the blood vessels, he thus accelerates blood flow to hair follicles.

The reason for this effect is still not clear, but Minoxidil, as it turned out in the research process, slows and stops hair loss, stimulates the growth of normal, healthy follicles. This effect, usually vary from patient to patient. Full confirmation stimulate hair growth of the drug was obtained when the drug is manufactured specifically for use on the surface of the head. Minoxidil has been used for more than 15 years in clinical trials and patients, revealing itself as a safe and very effective tool for treating hair loss.

Currently, the most famous (and most expensive) versions of the drug using Minoxidil manufactured by Pharmacia and Upjohn, "under the brand name Regaine (Regeyn) in Europe, the U.S. and certain other countries - under the brand name Rogaine (Rougeyn). The same products based on Minoxidil produced by other manufacturers in the non-proprietary forms for sale, and are cheaper. Drugs on the basis of Minoxidil for the treatment of baldness intended for external use only. Put them on carefully dried skin of the head at a dose of 1 ml 2 times a day, starting from the center of the affected area. The drug used in the same dose regardless of the size of affected areas.

The total daily dose should not exceed 2 ml. Side effects of these drugs can be expressed in redness, burning, peeling of the application, possible allergic reactions in rare cases, a change in blood pressure, a sense of palpitations, shortness of breath, swelling, headaches and dizziness.

atrophic alopecia (or psevdopelada) is characterized by the appearance of individual foci of atrophic formations on the hairy scalp and hair loss; Congenital alopecia - resistant form of baldness, manifested at birth; generalized alopecia is characterized by a complete absence of hair on all skin; alopecia (or circular alopecia), alopecia is hair loss on a clearly marked (usually round) section of the head;

Greenland alopecia, this type of hair loss usually associated with a traumatic impact on the hairy part of the skull, disruption of the structure of the scalp; diffuse alopecia - baldness uniform over the entire area of the head; Premature hair loss is characterized not justified in the early (25-30 years), loss of hair; Age alopecia after 50-60 years, which is considered the norm, but not us; Hippocrates noticed that eunuchs do not bald. Later the same circumstance mentioned by Aristotle. So what's the deal, and the case in the next, the principal male sex hormone testosterone is produced in the male testes, it is responsible for sexual behavior, muscle development, and at the end of that man is not a woman. But testosterone is not way does not affect hair growth. The main culprit early male pattern baldness is dihydrotestosterone (DHT), a hormone that in turn is a product of metabolism enzyme 5-alpha reductase and testosterone (ie testosterone 5-alpha reductase = DHT). Androgenetic alopecia in men, usually develops in the presence of normal levels of androgens in the blood, but in the presence of so-called "peripheral androgenizma. This term was first proposed in 1973 by K. D. Bingham. He proved that in the balding areas of the sensitivity of hair follicles DHT receptors and activity of enzymes involved in its conversion from testosterone is much higher than in non-balding. However, in the hair follicles was also discovered another enzyme (aromatase), which has the opposite effect and transforming testosterone into estrogens (female) hormones. In women, this enzyme is several times greater than that of men, in part, why women are not completely bald like men. Hair follicles, depending on the sensitivity of their receptors are divided into androgenchuvstvitelnye (on top of the head) and insensitive (in the bottom-back of the head). It is believed that the sensitivity of the hair follicle to androgens laid genetically - people born with a genetic defect reductase, just not when I do not suffer from prostatic hyperplasia and androgenic alopecia. That sensitivity receptor apparatus of hair follicles to DHT causes all subsequent pathological changes. In susceptible hair follicles of the scalp DHT binds to androgen receptors, after which the complex of hormone - receptor activates the genes responsible for the consistent transformation of large terminal follicles in the follicles of smaller size. The hair follicle is slowly declining, miniatyuriziruetsya and gradually replaced by connective tissue. As a result of such transformations are, respectively, a gradual decrease in the diameter of the rod of the growing hair. Instead precipitated the terminal hair starts to grow hair weakened (or vellus), shortened their life cycle. Phasing out the hair growth forms alopecia.